Topic: Group verb,

Best Answer Explained in Below-:

The phrase "ran out of" is idiomatic and is commonly used to indicate that someone has exhausted a limited resource. In the context of the sentence, the resource in question is patience. When we say that someone "ran out of patience," it means they have reached the limit of their tolerance or ability to remain calm in a frustrating situation, which directly correlates with them eventually losing their temper.

In contrast, the other options do not fit the context of the sentence in relation to patience:
- **A) ran into** typically means to encounter something unexpectedly, which isn't relevant to the concept of losing patience.
- **B) ran over** generally refers to moving across something or being physically active, which doesn't convey the idea of having a finite amount of patience.
- **C) ran away from** suggests avoidance or fleeing from a situation, which again does not pertain to the exhaustion of emotional capacity like patience.

Therefore, "ran out of" perfectly captures the intended meaning of the sentence by illustrating that the sister has exhausted her ability to remain patient before losing her temper.